Shrivatsa Hegde

Hello, I'm Shrivatsa Hegde

A Bioinformatician specializing in Molecular Docking, Cancer Genomics & Computational Biology

Molecular Docking Cancer Genomics NGS Analysis Machine Learning Drug Discovery

Experience

3+

Years in Bioinformatics

Publications

2

Published Papers

Projects

5+

Research Projects

Technical Skills

→ Programming: R, Python, Bash, C
→ Libraries: Pandas, NumPy, ggplot2, Biopython
→ Data Analysis: Statistical modeling, pathway analysis
→ Platforms: Linux, HPC environments, Git

Research Focus

→ Drug Discovery & Molecular Docking
→ Cancer Genomics & Oncology
→ Machine Learning in Bioinformatics
→ Gene Expression & NGS Analysis

Featured Project

PTK2/FAK in Breast Cancer

Comprehensive computational analysis of PTK2 protein expression across breast cancer subtypes, identifying correlations with tumor stemness, proliferation scores, and epithelial-to-mesenchymal transition (EMT). Applied gene expression profiling, pathway enrichment analysis, and statistical modeling.

Gene Expression Pathway Enrichment Breast Cancer R & Python

My Resume

Experience

Research Assistant

October 2023 – November 2024

Investigated molecular docking, modeling, and gene expression in depth. Published a paper on the computational approach to studying the effects of phytochemicals on cancer. Conducted gene expression studies including expression matrices and identifying differentially expressed genes.


→ Publication Link (Frontiers in Oncology)

Bioinformatics Intern

December 2022 – February 2023

Applied BioNLP techniques to identify and analyze biomedical named entities. Developed a foundation in machine learning and its tools within bioinformatics research.


→ Indian Institute of Technology Guwahati

Pharmacovigilance Intern

July 2022 – August 2022

Drug safety monitoring, adverse event reporting, signal detection, risk assessment, and regulatory compliance in drug safety. Gained insights into global drug safety regulations.


→ Edutech Life Pvt Ltd
Education

M.Sc. in Bioinformatics

October 2021 – August 2023

SGPA: 8.13


→ JSS Academy of Higher Education and Research

B.Sc. in Chemistry, Botany, Zoology

June 2017 – October 2020

Result: 71.3%


→ MES's M.M. Arts And Science College, Sirsi

Pre-University

June 2015 – April 2017

Result: 73%


MHN Government PU College, Kolgeebes

My Publications

Original Research Article
17 September 2024

Targeting FAK, VEGF, and MTA 1 Proteins with Terminalia elliptica: A Computational Approach for Anticancer Activity

Bhargav Shreevatsa, Shrivatsa Hegde, Prakruthi V, Chandan D, Anisha Jain, Tanveer Wani, Samudyata Math, Chandan Shivamallu, Shiva Prasad Kollur

→ Frontiers in Oncology
Book Chapter
30 September 2024

Application of Microbial Technique for the Synthesis of Organic Acid from Different Agrobiomasses

Karan Kumar, Shrivatsa Hegde, A.R. Ramyakrishna, Anweshan, Vijayanand S. Moholkar

→ Agricultural Biomass for the Synthesis of Value-Added Materials (Taylor & Francis)

My Projects

Dissertation

PTK2/FAK Crosstalk & Menopausal Status in Breast Cancer

March 2023 – July 2023

In-depth computational analysis of PTK2 protein expression across various breast cancer subtypes. Identified significant correlations between PTK2 expression and tumor stemness, proliferation scores, and EMT. Applied gene expression profiling, pathway enrichment analysis, and statistical modeling using R and Python.


Gene Expression EMT Analysis R & Python

→ JSS Academy of Higher Education and Research, Mysuru
Summer Internship

Focal Adhesion Kinase as Target for Terminalia elliptica

November 2022 – February 2023

Explored the therapeutic potential of natural products in breast cancer treatment. Identified chebulagic acid as a promising lead molecule using molecular docking, with superior binding affinity to FAK compared to standard drug podophyllotoxin.


Molecular Docking Virtual Screening Drug Discovery

→ JSS Academy of Higher Education and Research, Mysuru

About Me

I am a passionate and driven bioinformatician with a diverse educational background spanning chemistry, biology, and computational sciences. My expertise encompasses data analysis and proficiency in multiple programming languages including Linux/Bash, Python, R, and C, along with strong skills in data manipulation libraries such as Pandas and NumPy.

I am keenly interested in exploring the applications of machine learning and artificial intelligence in bioinformatics. My passion lies in leveraging these skills to tackle challenging problems and contribute to cutting-edge research and projects.

I'm always eager to collaborate on drug discovery, machine learning projects, research endeavors, and competitions. Feel free to reach out!

Open to Collaborate On

→ Drug discovery & molecular docking
→ Cancer research & genomics
→ Machine learning in bioinformatics
→ Research publications & competitions
→ Freelance bioinformatics consulting
→ Open science initiatives

Skillset & Technologies
Python Python
R R
Bash Bash / Linux
C C
TensorFlow TensorFlow
Git Git
HTML HTML
CSS CSS
Excel
PowerPoint
Word
Terminal / HPC

My Certifications

🧬

Bioinformatics for Biologists: Introduction to Linux, Bash Scripting, and R

Linux essentials, file system navigation, data manipulation, and automating data processing with shell scripts for export to R for analysis and visualization.

Linux Bash R

→ View Certificate (FutureLearn)
🔬

Next Generation Sequencing Certificate Course

Advanced expertise in NGS technology — a comprehensive experience to develop essential skills in analyzing complex genomic data.

NGS Genomics

→ Biogrademy
🐍

Data Analysis with Python: Zero to Pandas

Step-by-step approach to learning Python for data analysis — skills and knowledge necessary to analyze data and extract valuable insights.

Python Pandas NumPy

→ View Certificate (Jovian)
🐧

Complete Linux Training Course

An excellent resource for those who are new to Linux — learning, understanding, and practicing its various aspects and functionalities.

Linux System Admin

→ View Certificate (Udemy)
🧪

Genetics and Next Generation Sequencing for Bioinformatics

A great kickstart for learning the ins and outs of Next Generation Sequencing with Galaxy. Recommended for everyone in this field!

Galaxy NGS Genetics

→ View Certificate (Udemy)
⚗️

Bioinformatics: Learn Docking & Molecular Dynamics Simulation

A great way to begin learning molecular docking and simulation. A must-have skill for everyone in this field.

Docking MD Simulation

→ View Certificate (Udemy)

Interactive Bio Tools

Use these tools to perform common bioinformatics analyses directly in your browser — no software installation needed.

Pairwise Sequence Alignment

Compare two protein sequences (single-letter amino acid codes) and visualize similarity.

→ Results will appear here after clicking Run Alignment.

Uses Needleman-Wunsch global alignment (JavaScript implementation)

Ramachandran Plot Demo

Visualize a simulated Ramachandran plot — upload a PDB file or use the demo data to see dihedral angle distributions.

→ Click Generate Plot to visualize dihedral angles.

Demo uses simulated Ramachandran data. For full analysis, use the Shiny App.

Full R Shiny Application

For the complete interactive bioinformatics toolkit (Ramachandran plot with real PDB parsing, alignment with scoring matrices, and more), visit the full Shiny application:

Get In Touch

I'd love to hear from you about potential collaborations, research opportunities, or just to chat about bioinformatics!

Contact Details
Email
shrivatsahegde62@gmail.com
Phone
+91 7899502822
+91 9739767884